Sterol Metabolism
نویسندگان
چکیده
منابع مشابه
Oxidative Demethylation in Sterol Metabolism
Oxidative demethylation of 4-methyl sterols by rat liver microsomes has been shown to be inhibited by low levels of NADH. Using snake venom-treated microsomes to remove endogenous NADH-utilizing activities, we observed inhibition of overall demethylation at concentrations of NADH as low as 2.5 p ~ . At 20 p~ NADH, overall demethylation had been reduced to 60% of optimal activity. In the presenc...
متن کاملSterol Biosynthesis and Metabolism in Marine Invertebrates
The present state of knowledge on the ability of marine invertebrate animals to synthesise and metabolise sterols is reviewed. While animals from some phyla have a limited ability to synthesise sterols .a other groups of invertebrates are apparently incapable of sterol synthesis. It appears likely that much of the sterol of invertebrates originates from algae either in the plankton or living as...
متن کاملSterol metabolism studies in the rat. Effects of primary bile acids (sodium taurochenodeoxycholate and sodium taurocholate) on sterol metabolism.
Sterol metabolism studies using a combination of isotopic and chromatographic procedures were carried out in rats fed either a low-cholesterol stock diet or a stock diet containing 0.1% cholesterol. The primary bile acids, sodium taurochenodeoxycholate and sodium taurocholate, were added to the stock diets at a level of 0.5%, as required. Feeding sodium taurochenodeoxycholate and sodium tauroch...
متن کاملSterol carrier protein 2 gene transfer changes lipid metabolism and enterohepatic sterol circulation in mice.
BACKGROUND & AIMS Sterol carrier protein 2 (SCP-2) enhances sterol cycling and facilitates cholesterol translocation between intracellular organelles and plasma membrane in cultured cells, including hepatocytes. We examined the role of SCP-2 in hepatic cholesterol and lipid trafficking through the sinusoidal and canalicular secretory pathways of the liver in vivo. METHODS Recombinant adenovir...
متن کاملCholesterol absorption efficiency and sterol metabolism in obesity.
Role of enterohepatic cholesterol metabolism in obesity-induced increase of cholesterol synthesis was studied in healthy lean (BMI <24) and overweight (BMI >31) subjects by measuring serum lipids (including plant sterols, cholestanol and cholesterol precursors), cholesterol absorption % (double-label method), sterol balance and biliary lipids. New aspects of sterol metabolism in obesity were as...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1960
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)76922-1